GIS is considered an important technique as well as a prerequisite for cost effective mineral exploration and determination of high potential areas. The purpose of this research is to determine high potential iron zones for detailed exploration using index overlay GIS method. Index Overlay was used to combine the geology, topography (scale: 1:1,000), lineaments, remote sensing (ASTER and ETM+) and geochemical data. Appropriate weights were allocated to each layer based on the significance of each data layer. Concentration-area fractal method was applied to data acquired from trenches in order to isolate iron anomalies and add them to the geochemical layer. Evaluation of the information layers along with fractal analysis, differentiated three geochemical iron populations. By combining the information layers obtained from GIS, high potential zones were determined. Regions with codes 1, 2 and 3 are the most promising areas, respectively, and are proposed for more detailed exploration and drilling.